{"id":34771,"date":"2009-10-28T11:17:22","date_gmt":"2009-10-28T11:17:22","guid":{"rendered":"https:\/\/joomhost1.com\/leishvet\/?p=34771"},"modified":"2025-09-09T11:18:06","modified_gmt":"2025-09-09T11:18:06","slug":"canine-leishmaniosis-directions","status":"publish","type":"post","link":"https:\/\/joomhost1.com\/leishvet\/canine-leishmaniosis-directions\/","title":{"rendered":"Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis"},"content":{"rendered":"

[vc_row row_height_percent=”0″ override_padding=”yes” h_padding=”2″ top_padding=”2″ bottom_padding=”2″ overlay_alpha=”50″ gutter_size=”3″ column_width_percent=”100″ shift_y=”0″ z_index=”0″ content_parallax=”0″ uncode_shortcode_id=”160017″][vc_column column_width_percent=”100″ position_vertical=”middle” align_horizontal=”align_center” gutter_size=”2″ back_color=”color-971813″ overlay_alpha=”50″ radius=”std” shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1\/1″ uncode_shortcode_id=”144309″ back_color_type=”uncode-palette”][vc_custom_heading auto_text=”yes” heading_semantic=”h1″ text_size=”h4″ uncode_shortcode_id=”118537″]This is a custom heading element.[\/vc_custom_heading][vc_column_text uncode_shortcode_id=”188566″]Solano-Gallego L,<\/a> Koutinas A,<\/a> Mir\u00f3 G,<\/a> Cardoso L,<\/a> Pennisi MG,<\/a> Ferrer L,<\/a> Bourdeau P,<\/a> Oliva G,<\/a> Baneth G<\/a>
\n(Vet Parasitol.<\/a> 2009, 165(1-2):1-18)<\/strong><\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=”0″ override_padding=”yes” h_padding=”2″ top_padding=”1″ bottom_padding=”2″ overlay_alpha=”50″ gutter_size=”3″ column_width_percent=”100″ shift_y=”0″ z_index=”0″ content_parallax=”0″ uncode_shortcode_id=”610496″][vc_column column_width_percent=”100″ gutter_size=”2″ overlay_alpha=”50″ shift_x=”0″ shift_y=”0″ shift_y_down=”0″ z_index=”0″ medium_width=”0″ mobile_width=”0″ width=”1\/1″ uncode_shortcode_id=”121806″][vc_column_text uncode_shortcode_id=”153610″ el_class=”text-justify”]Canine leishmaniosis (CanL) due to Leishmania infantum<\/em> is a life threatening zoonotic disease with a wide distribution in the Old and New World and increasing importance also in non-endemic areas. The purpose of this report is to present a consensus of opinions on the diagnosis, treatment, prognosis and prevention of CanL in order to standardize the management of this infection. CanL is a disease in which infection far exceeds clinical disease due to the high prevalence of subclinical infection among endemic canine populations. The most useful diagnostic approaches include serology by quantitative techniques and PCR. High antibody levels are associated with severe parasitism and disease and are diagnostic of clinical leishmaniosis. However, the presence of lower antibody levels is not necessarily confirmatory for the disease and further work-up is necessary to confirm CanL by other diagnostic methods such as cytology, histopathology and PCR. We propose a system of four clinical stages, based on clinical signs, clinicopathological abnormalities and serological status. Suitable therapy and expected prognosis are presented for each of the stages. The combination of meglumine antimoniate and allopurinol is the first line therapeutic protocol. However, although most dogs recover clinically after therapy, complete elimination of the parasite is usually not achieved and infected dogs may eventually relapse. Follow-up of treated dogs with blood counts, serum biochemistry, urinalysis, serology and PCR is essential for prevention of relapses. Protection against sand fly bites by topical insecticides is effective in reducing infection, and recent development of vaccines has indicated that prevention by vaccination is feasible.<\/p>\n

\n

N.B.: for a reprint of the article please contact leishvet@ucm.es<\/a>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column width=”1\/1″][uncode_block id=”34686″][\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

Solano-Gallego L, Koutinas A, Mir\u00f3 G, Cardoso L, Pennisi MG, Ferrer L, Bourdeau P, Oliva G, Baneth G <\/p>\n

(Vet Parasitol.<\/strong> 2009, 165(1-2):1-18)<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"inline_featured_image":false,"footnotes":""},"categories":[91],"tags":[92],"table_tags":[],"class_list":["post-34771","post","type-post","status-publish","format-standard","hentry","category-publications","tag-leishvet-publications"],"yoast_head":"\nDirections for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis - LeishVet<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/joomhost1.com\/leishvet\/canine-leishmaniosis-directions\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Directions for the diagnosis, clinical staging, treatment and prevention of canine leishmaniosis - 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